Depression and addiction are two common mental health disorders, but when they collide, it’s more than a bad day. These two conditions often show up together as co-occurring disorders, fueling each other in a relentless loop that can feel impossible to escape.
At iRely Recovery in Los Angeles, we tackle depression and addiction head-on with an integrated treatment plan that addresses how these conditions influence and exacerbate one another. We break the cycle by addressing the root of the problem, not just treating its symptoms.
KEY POINTS
- Depression and addiction often co-occur, feeding off of each other and turning manageable struggles into crises.
- Both depression and addiction can share root causes, like trauma, genetics, and stress, that can increase the risk of developing both.
- Symptoms of depression and addiction can overlap, blurring the lines between which symptoms are caused by which disorder.
- You can’t treat one and ignore the other, which is why dual diagnosis care is essential to true healing.
DUAL DIAGNOSIS TREATMENTS
What Is Depression?
Depression is more than feeling “blue.” It’s a full-body shutdown that affects your emotional, mental, and physical states. It drains your energy, hijacks your thoughts, and disconnects you from the world around you. According to a 2023 national survey, nearly 30% of adults in the U.S. have been diagnosed with depression.[1]
Common symptoms of depression can include:[2]
- Sadness, irritability, or hopelessness
- Loss of interest in what used to make you happy
- Sleeping too much or too little
- Eating too much or too little
- Feeling like you and what you do doesn’t matter
- Brain fog or poor memory
- Suicidal ideation or attempts
Symptoms like these that persist for more than a few weeks go far beyond “just being in a funk.” While everyone feels down occasionally, clinical depression is a sustained pattern that disrupts daily functioning and well-being.
Addiction and Interaction with Depression
Depression makes you want to disappear. Substances can offer a temporary escape, leading to a cycle of self-medication. You may drink or use drugs to numb your emotions or quiet your mind — but over time, this “relief” rewires your brain, making you dependent just to feel okay. Addiction also disrupts brain chemistry, worsening depressive symptoms until you’re chasing a high that’s always out of reach.
Both addiction and depression share risk factors like stress, trauma, and genetic predisposition. People with close relatives who have depression are two to three times more likely to develop it themselves.[3] The same holds true for dysfunctional or abusive environments, which raise the risk of both addiction and mental illness.[4]
Brain imaging studies confirm that the parts of the brain involved in mood, sleep, and decision-making are functionally different in people with depression.[5] Other research shows that disruptions in these same brain regions are tied to addiction and impulsive behaviors.[6]
The numbers say it all. Nearly 50% of people with a mental illness also struggle with addiction — and vice versa.[7] Those with mood disorders are twice as likely to develop substance use disorders, and over 17 million U.S. adults are living with both conditions.[8,9]
Sorting out which came first — depression or addiction — and which symptoms belong to which disorder can be confusing. But treating them separately misses the point. Recovery requires a dual diagnosis approach that addresses both conditions together to create meaningful, lasting change.
Different Types of Depression
Major depressive disorder is what we commonly refer to as “depression,” but there are other types of depression to be aware of.[10]
- Persistent depressive disorder: A long-lasting depressive episode that can be more persistent than major depressive disorder with less-severe symptoms. It typically lasts two years or longer and can wear you down over time.
- Seasonal depression: Also known as seasonal affective disorder, this form of depression occurs with seasonal changes, usually in fall and winter, and tends to improve with more daylight in spring and summer.
- Bipolar depression: Marked by extreme highs and lows (mania or hypomania and depression), bipolar depression is a cyclical mood disorder with episodes that can severely impact daily life.
- Perinatal depression: More intense than typical “baby blues,” this type affects women during pregnancy or after childbirth and can interfere with bonding and caregiving.
- Premenstrual dysphoric disorder (PMDD): An extreme form of PMS characterized by mood swings, irritability, and depression that occur before menstruation.
- Disruptive mood dysregulation disorder (DMDD): A childhood disorder with severe temper outbursts and chronic irritability, going beyond normal mood swings or tantrums.
Depression and Substance Use Dual Diagnosis Treatment Programs in Los Angeles
At iRely Recovery, we rely on evidence-based, life-changing modalities that help you overcome your struggles. Here are some of the treatment options for practical and holistic therapy for depression and substance use disorder:
- Cognitive behavioral therapy (CBT): Helps challenge your inner critic, rewrite negative thought loops, and make conscious, healthy choices.
- Dialectical behavioral therapy (DBT): Balances emotional highs and lows while teaching tools to cope with intense feelings and impulsive behaviors.
- Individual therapy: A one-on-one space to process trauma, understand your story, and rebuild through personalized strategies.
- Family therapy: Repairs damaged connections and helps loved ones navigate the healing process together with empathy and structure.
- Group therapy: Offers connection, support, and shared understanding in a space where others are walking a similar path.
- Recovery-oriented treatment: Focuses on building purpose, clarity, and a sustainable sober lifestyle.
- Acceptance and commitment therapy (ACT): Teaches how to move forward even in the presence of pain, guided by values and meaning.
- Somatic experiencing therapy: Releases trauma stored in the body and helps you feel physically grounded and safe again.
- Adventure therapy: Builds confidence, connection, and healing through outdoor activities that challenge and inspire.
- Trauma-informed care: Ensures every step of treatment respects your lived experience and avoids retraumatization.
- Experiential therapy: Uses art, music, and movement to help you express feelings that may be difficult to verbalize.
- Mindfulness-based therapy: Cultivates awareness and calm by learning to observe emotions and thoughts without judgment.
- Motivational interviewing (MI): Encourages honest reflection and empowers you to find your own reasons and readiness for change.
Frequently Asked Questions About Addiction and Depression Treatment Centers in Los Angeles
Why Does Dual Diagnosis Require Special Treatment?
Dual diagnosis means you’re dealing with a mental health disorder and substance use disorder at the same time. Treating each condition individually overlooks the ways these conditions interact with one another, but dual diagnosis treatment addresses the interplay between them for genuine healing.
Is Medication Part of Treatment for Depression and Addiction?
Possibly. Medications can be a big help in treating depression and addiction, but they’re not a one-size-fits-all solution. We’ll work with you to determine what best supports your healing, whether that includes medication or not.
How Long is Dual Diagnosis Treatment for Depression and Addiction?
It depends. Many programs are a few months long, but your treatment can be longer or shorter based on your specific challenges, goals, and progress.
Will I Ever Feel Like Myself Again?
The “old” you is struggling with depression and addiction. Recovery is about moving past that and becoming a healthier, stronger person. The goal isn’t just to feel okay, but to build a life you want to be present in.
Sources
[1,2] What is depression?. Psychiatry.org – What Is Depression? (n.d.). https://www.psychiatry.org/patients-families/depression/what-is-depression
[3] Genetics of Brain Function. (n.d.). Major Depression and Genetics. https://med.stanford.edu/depressiongenetics/mddandgenes.html
[4] Negele, A., Kaufhold, J., Kallenbach, L., & Leuzinger-Bohleber, M. (2015). Childhood trauma and its relation to chronic depression in adulthood. Depression research and treatment. https://pmc.ncbi.nlm.nih.gov/articles/PMC4677006/
[5] U.S. Department of Health and Human Services. (n.d.-a). Depression. National Institute of Mental Health. https://www.nimh.nih.gov/health/topics/depression
[6] Substance Abuse and Mental Health Services Administration (US). (n.d.). The Neurobiology of Substance Use, misuse, and addiction. Facing Addiction in America: The Surgeon General’s Report on Alcohol, Drugs, and Health [Internet]. https://www.ncbi.nlm.nih.gov/books/NBK424849/#:~:text=Well%2Dsupported%20scientific%20evidence%20shows%20that%20disruptions%20in%20three%20areas,actions%2C%20emotions%2C%20and%20impulses.
[7] U.S. National Library of Medicine. (n.d.). Common comorbidities with Substance Use Disorders Research Report. National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK571451/
[8] Mental illness and addiction: Facts and statistics. CAMH. (n.d.). https://www.camh.ca/en/driving-change/the-crisis-is-real/mental-health-statistics
[9] 2020 National Survey on Drug Use and Health (NSDUH) releases. SAMHSA.gov. (n.d.). https://www.samhsa.gov/data/data-we-collect/nsduh-national-survey-drug-use-and-health/national-releases/2020
[10] What is depression?. Psychiatry.org – What Is Depression? (n.d.). https://www.psychiatry.org/patients-families/depression/what-is-depression

